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Company Profile: Charles River Laboratories International, Inc. (CRL)

CRL insider trades (13 months) →

$351.87 +3.94% vs. previous close · Market cap $16.95B

Today's multi-factor rank: 383 of 461 · see the ranking

Momentum
7.1/10
Value
3.7/10
Growth
3.6/10
Quality
3.5/10
Multifactor
4.5/10

Market and Valuation

Price & Market

Prev Close Price:$338.54
Open:$339.88
Day's Low:$339.00
Day's High:$356.35
Bid / Ask:-
Market Cap:16.95B
Enterprise Value:19.05B

52-Week Range

52-Week Low:$146.20
52-Week High:$379.63
Current position in 52-week range
52w Low-52w High
50-Day Avg:$302.78
200-Day Avg:$222.36

Volume

Volume Today:1,509,158
Avg Volume (3m):1,047,645
Avg Volume (10d):1,514,710
52-Week Change:+90.35%
vs S&P 500, 52 weeks:-
Beta:1.34

Valuation Multiples

P/E (trailing):n/a (loss)

Diluted EPS for the last 12 months: the four quarters ended Jun 27, 2026, from the accounts filed with the SEC on Aug 5, 2026. With negative EPS a P/E means nothing, so it is not shown.

P/E (forward):27.61
PEG Ratio:0.12
Price / Book:5.91
Price / Sales (TTM):4.24
EV / Revenue:4.76
EV / EBITDA:22.44

Dividends

Current yield:-
Annual Dividend Rate:-
Dividend Trailing:$0.00
Yield Trailing:0.00%
5-Year Avg Yield:-
Payout Ratio:0.00%
Last Ex-Dividend Date:-

Valuation Context

P/E vs sector (indicative)

Most Recent Quarter:-
Fiscal Year (Next):-

Loading historical OHLCV database...

Financial Statements TTM (Trailing 12 Months)

Income Statement

Total Revenue (TTM):4.00B
Gross Profit:1.38B
EBITDA:849.12M
Net Income (TTM):−238.46M
Rev Growth (YoY):-2.70%
Earnings Growth (YoY):-
Quarterly earnings growth (YoY):-

Margins

Gross Margin:-
EBITDA Margin:-
Operating Margin:-
Net Margin:-

Per Share

EPS Trailing (TTM):$-4.79

Diluted EPS for the last 12 months: the four quarters ended Jun 27, 2026, from the accounts filed with the SEC on Aug 5, 2026. With negative EPS a P/E means nothing, so it is not shown.

EPS Forward (Est.):$12.75
Revenue Per Share:$81.86
Cash Per Share:-
Book Value:$59.50
Last Dividend:-
Ex-Dividend Date:-
Last Split:-

Balance Sheet & Liquidity

Total cash:192.02M
Total Debt:3.03B
Net Debt (Debt - Cash):2.84B
Debt / Equity:105.05%
Current Ratio:1.35
Quick Ratio:0.80

Cash Flows

Operating Cash Flow:582.15M
Free Cash Flow (FCF):468.86M
FCF Yield (FCF / Market Cap):-
Enterprise Value:19.05B
EV / Revenue:4.76
EV / EBITDA:22.44

Profitability

ROE (Return on Equity):-7.52%
ROA (Return on Assets):4.11%
P/E (trailing):n/a (loss)
P/E (forward):27.61
Price / Book:5.91
PEG Ratio:0.12
52-Week Change:+90.35%
S&P 500 change, 52 weeks:+11.37%

Historical Evolution (Last 4 Years)

Income Statement

Balance Sheet

Cash Flow

EPS and Earnings Per Share

Key EPS Metrics

EPS Trailing (TTM):$-4.79

Diluted EPS for the last 12 months: the four quarters ended Jun 27, 2026, from the accounts filed with the SEC on Aug 5, 2026. With negative EPS a P/E means nothing, so it is not shown.

EPS Forward (Est.):$12.75
P/E (forward):27.61
PEG Ratio:0.12

Growth and Margins

Earnings Growth YoY:-
Quarterly Earnings Growth YoY:-
Rev Growth YoY:-
Net Margin:-
Gross Margin:-
EBITDA Margin:-

Per Share

Revenue Per Share:$81.86
Cash Per Share:-
Book Value:$59.50

Cash Flows (TTM)

Free Cash Flow:468.86M
Operating Cash Flow:582.15M
EBITDA:849.12M
Total Revenue (TTM):4.00B
Net Income (TTM):−238.46M
Fiscal Year (Last):-

EPS Surprise History - Last 4 Quarters

Actual vs. Analyst Estimates · Green = beat expectations · Red = missed

Quarter Period Actual EPS Estimated EPS Difference Surprise % Currency

Ownership Structure

Ownership Distribution

% Insiders:-
% Institutional:-
% Inst. (of Float):-
No. of Institutions:-
Visual distribution
InsidersInstitutionalFree Float

Shares & Short Interest

Shares Outstanding:48,167,730
Float (free shares):47,196,558
Short interest (shares):2,834,023
Short % of float:-
Short Ratio (days to cover):2.77
Short interest, prior month:-
Short Interest Date:-

Governance Score (1=Best, 10=Worst)

Overall risk:-
Audit Risk:-
Board risk:-
Compensation Risk:-
Shareholder rights risk:-

Top Institutional Holders

Position Change: ▲ Increased · ▼ Reduced · = Unchanged

Organization Report Date % Shares No. Shares Value (USD) Change %

Top Mutual Funds

Position Change: ▲ Increased ▼ Decreased = Unchanged

Fund Report Date % Shares No. Shares Value (USD) Change %

Recent Insider Trades

Executive / Insider Title Date Action Shares

Options Chain

CALLS

StrikeLastBidAskVol.O.I.IV

PUTS

StrikeLastBidAskVol.O.I.IV

Charles River Laboratories International, Inc. (CRL) SEC filings: 10-K, 10-Q and 8-K

Direct links to financial reports filed with the SEC.

Type Date Official link
8-K2026-09-24View filing ↗
10-Q2026-08-05View filing ↗
SD2026-05-11View filing ↗
8-K2026-05-07View filing ↗
ARS2026-03-31View filing ↗
8-K2026-02-25View filing ↗
10-K2026-02-18View filing ↗
8-K2026-01-13View filing ↗
8-K2026-01-09View filing ↗
8-K2025-12-03View filing ↗

Company and Executive Profile

Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization; and Medigen Vaccine Biologics Corp for developing next-generation multivalent enterovirus vaccine, enhance global regulatory readiness, and support IND-enabling non-clinical studies. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.

General Information

Headquarters:United States
City:Wilmington
Employees:18,300
Sector:Healthcare
Industry:Diagnostics & Research
Website:-

Key Executives

NameTitleAgeTotal pay
Ms. Birgit GirshickCEO & Director551.77M
Mr. Michael Gunnar KnellCorporate Senior VP & Chief Accounting Officer48912,225
Mr. Joseph W. LaPlume J.D.Corporate Executive Vice President of Corporate Development & Strategy511.25M
Ms. Victoria L. CreamerCorporate Executive VP & Chief People Officer551.23M
Mr. Glenn G. Coleman CPACorporate Executive VP & CFO57-
Mr. Mark MintzCorporate EVP, Chief Information Officer & Global Shared Services51-
Mr. Todd SpencerCorporate Vice President of Investor Relations--
Ms. Kerry DaileyCorporate Senior VP & Chief Legal Officer--

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Charles River Laboratories International, Inc. (CRL): Quantitative Analysis

Charles River Laboratories International, Inc. (CRL) — Healthcare — Diagnostics & Research. CRL is in the S&P 500 today. Model factor scores and market data, recalculated every trading day.

So far in 2026, CRL has returned +76.4% against +11.4% for the S&P 500 (SPY): total return, dividends included on both sides, from Dec 31, 2025 to Nov 3, 2026.

CRL ranks 383 of 461 on today's multifactor score, and 49 of the 55 Healthcare companies that score. Its strongest factor is momentum (Z 1.28, ranked 46 of 494); its weakest is quality (Z -0.92, ranked 448 of 468). Each factor ranks only the companies with data for it, and the multifactor score only those with all four: that is why the totals differ.

Factor scores

The Z-Score is how many standard deviations the company sits from the index average: 0 is average, positive is better than average, negative is worse.

FactorZ-ScoreRank
Multifactor-0.319383 of 461
Momentum1.27946 of 494 ↑20
Value-0.808476 of 489 ↓3
Quality-0.915448 of 468 ↓2
Growth-0.831468 of 489

Market data

MetricValue
Price$351.87
Market Cap16.95B
Forward P/E (estimate)27.61
Revenue (last 12 months)4.00B
Price / book5.91
Book value per share$59.50
52-week range$146.20 – $379.63
Dividend yield0.00%
Beta1.34
Average volume1,047,645
Shares outstanding48.17M
Short interest (% of float)6.86% (as of Oct 15, 2026)

When does CRL report earnings? 12 of its last 12, before the open →

What are CRL insiders doing? 101 transactions filed with the SEC, of them 2 buys and 14 sells, the last one on Oct 22, 2026 →

CRL latest SEC filings

Filing dates on EDGAR, the SEC's public registry. All CRL filings on EDGAR.

Guides: How to read a Quant500 company page · What the S&P 500 is · P/E ratio explained · 10-K, 10-Q and 8-K · all guides

Frequently asked questions about Charles River Laboratories International (CRL)

When does Charles River Laboratories International report earnings?

According to Nasdaq's public calendar (checked on Nov 4, 2026), Charles River Laboratories International will report its next earnings on Nov 4, 2026, before the US market opens. The date is announced by the company itself and can change. Of its last 12 earnings announcements: 12 before the open (SEC filings through Aug 5, 2026). CRL earnings dates and times, quarter by quarter →

Where does Charles River Laboratories International rank on Quant500?

In the Nov 3, 2026 multi-factor ranking, Charles River Laboratories International ranks 383 of 461, and 49 of the 55 Healthcare companies that score. The ranking orders S&P 500 companies by the average of four factors (momentum, value, quality and growth) and is recalculated every trading day. It is a model output, not investment advice. The full ranking → How it is calculated →

Have Charles River Laboratories International insiders bought or sold shares?

The latest open-market purchase of Charles River Laboratories International shares filed with the SEC (Form 4) was on Sep 30, 2026, by an officer, for $3k. The latest sale was on Oct 22, 2026, by a director, for $8.4M. In total, from August 2025 through Nov 3, 2026: 2 purchases and 14 sales by directors, officers and large shareholders. All CRL insider trades →

What sector is Charles River Laboratories International in, and which index?

Charles River Laboratories International is classified in the Healthcare sector (industry: Diagnostics & Research), per the data provider's classification (similar to GICS, not identical). It is in the S&P 500 today. It is one of the 59 S&P 500 companies in that sector. Healthcare stocks →

What is behind these numbers

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Data as of Nov 3, 2026. Source: point-in-time SEC fundamentals and closing prices. Method and formulas are on the home page.

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